• Varying metabolic activity within a yeast colony
    Image courtesy of Dr. Kate Campbell, Ralser Lab, University of Cambridge
  • Localization of Erg1-GFP to lipid droplets in stationary phase cells
    Image courtesy of Sébastien Léon, Institut Jacques Monod/ CNRS - Paris, France.
  • Rap1-GFP and Calcofluor White staining of stationary phase cells.
    Image courtesy of M. Guidi, M. Ruault and A. Taddei, Institut Curie (Paris).
  • Pma1-mCherry and Vma1-GFP localization in mitotic cells.
    Image courtesy of M. Eastwood, Fred Hutch and M. Meneghini, University of Toronto.
  • CCCP-induced decrease of mitochondrial membrane potential (below) or control treatment (above) as measured by MitoLoc.
    Image courtesy of Dr. Jakob Vowinckel, Ralser Lab, University of Cambridge.
  • Large sized lipid droplets in aged wild-type BY4741 cells
    Large sized lipid droplets in aged wild-type BY4741 cells
    Image courtesy of D.K. Vijayan, R. Rajasekharan and M. Srinivasan, CSIR-CFTRI, India
  • Redistribution of Msn5 pools from the nucleus to the cytoplasm upon glucose deprivation.
    Image courtesy of H. Huang and A. Hopper, Ohio State University.
  • slideshow24-new
    Floccule of yeast rho0 cells expressing PTS1-GFP as a peroxisomal marker, stained with calcofluor white.
    Image courtesy of Dr. Jakob Vowinckel, University of Cambridge
  • S. cerevisiae membrane proteins visualized by RFP and GFP.
    Image courtesy of Masur. Wikimedia Commons.
  • Peroxisome (red) and mitochondrial (green) fission defects in vps1 fis1 double deletion strain transformed with FIS1.
    Image courtesy of S. Lefevre, S. Kumar and I. van der Klei, University of Groningen.
  • Yeast cells expressing TRK1/GFP.
    Image courtesy of V. Zayats and J. Ludwig, Center of Nanobiology and Structural Biology, AV CR.
  • The distribution of mtDNA (green) within the mitochondrial network (red).
    Image courtesy of Christof Osman and Peter Walter, University of California, San Francisco
  • The distribution of ER exit sites (ERES, green) within the ER (red).
    Image courtesy of A. Nakano and K. Kurokawa, RIKEN.
  • Cell, actin and nuclear morphology of yeast cells treated with DMSO (left) and poacic acid (right).
    Images courtesy of Hiroki Okada and Yoshikazu Ohya, University of Tokyo.
  • Colombo S and Martegani E
    Localization of active Ras in a wild type strain
    Image courtesy of S. Colombo and E. Martegani, University Milano Bicocca
  • Sectored Colonies
    Sectored colonies showing loss of silencing at the HML locus
    Image courtesy of Anne Dodson, UC Berkeley
  • Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red)
    Pma1p imaged using the RITE tagging system in mother (green) and daughter cells (red)
    Image courtesy of Dan Gottschling Ph.D., Fred Hutchinson Cancer Research Center
  • San1 strain visualized with FUN and calcofluor white
    San1 strain visualized with FUN and calcofluor white
    Image courtesy of the Bruschi lab, ICGEB, Trieste, Italy
  • Single MDN1 mRNAs detected by FISH
    Single MDN1 mRNAs detected by FISH
    Image courtesy of the Zenklusen Lab, Université de Montréal
  • Localization of Ace2-GFP to daughter cell nuclei
    Localization of Ace2-GFP to daughter cell nuclei
    Image courtesy of Eric Weiss, Ph.D. Northwestern University

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The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae along with search and analysis tools to explore these data, enabling the discovery of functional relationships between sequence and gene products in fungi and higher organisms.

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New & Noteworthy

  • Sign Up Now for the Next SGD Webinar: May 4th, 2016

    04/26/2016

    If you’re not already using YeastMine to answer all your questions about S. cerevisiae genes and gene products...you should be! SGD's YeastMine is a powerful search tool that can retrieve, compare, and analyze data on thousands of genes at a time, greatly reducing the time needed to answer real, practical research questions. Through YeastMine, questions such as "What proportion of plasma membrane proteins are essential?" or "How many different gene products physically interact with the... Read...
  • Chocolate and Coffee Too?

    04/20/2016

    Most of us know about yeast’s big part in making bread and booze. But those aren’t yeast’s only wonderful gifts. It also plays a big role in chocolate and coffee too. Is there anything this marvelous microorganism can’t do? A new study by Ludlow and coworkers in Current Biology set out to look at the strains involved in cacao and coffee fermentation. Unlike the extensively studied wine strains, these have mostly been ignored up until now. These... Read...
  • Lessons from Yeast: Poisoning Cancer

    04/06/2016

    In the book Dune, the mentat Thufir Hawat is captured by the evil Harkonnens and given a residual poison. He can only stay alive by getting a constant dose of the antidote. Once it is withdrawn, he will die. A new study in the journal GENETICS by Dodgson and coworkers shows that the same sort of thing can happen to yeast that carry an extra chromosome. In this case, certain genes on the extra chromosome turn... Read...
  • Apply Now for the 2016 Yeast Genetics & Genomics Course

    03/30/2016

    For almost 50 years, the legendary Yeast Genetics & Genomics course has been taught each summer at Cold Spring Harbor Laboratory. (OK, the name didn’t include “Genomics” in the beginning…). The list of people who have taken the course reads like a Who’s Who of yeast research, including Nobel laureates and many of today’s leading scientists. The application deadline is April 15th, so don’t miss your chance! Find all the details and application form here. This year's... Read...

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